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POLR2E Mouse Monoclonal Antibody [Clone ID: LBI3B5]

Product Specifications

Background

This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) POLR2E mouse monoclonal antibody, clone LBI3B5

Synonyms

HRPB25; hsRPB5; RPABC1; RPB5; XAP4

Gene Name

Homo sapiens RNA polymerase II, I and III subunit E (POLR2E), transcript variant 1, mRNA.

Gene ID

5434

UniProt

P19388

Conjugation

Unconjugated

Related Pathways

Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase

Field of Research

Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase

Dilution

WB 1:500~2000, IHC 1:150, FLOW 1:100, IF: 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

POLR2E

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=5434

Uniprot URL

https://www.uniprot.org/uniprot/P19388

Frequently Asked Questions

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