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Arginase 1 (ARG1) Mouse Monoclonal Antibody [Clone ID: LBI4E6]

Product Specifications

Background

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) ARG1 mouse monoclonal antibody, clone LBI4E6

Synonyms

OTTHUMP00000017209; arginase 1; liver-type arginase; type I arginase; arginase, liver

Gene Name

Homo sapiens arginase 1 (ARG1), transcript variant 2, mRNA.

Gene ID

383

UniProt

P05089

Conjugation

Unconjugated

Related Pathways

Arginine and proline metabolism, Metabolic pathways

Field of Research

Arginine and proline metabolism, Metabolic pathways

Dilution

WB 1:1000~2000, IHC 1:50, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

ARG1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=383

Uniprot URL

https://www.uniprot.org/uniprot/P05089

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