NMNAT1 Mouse Monoclonal Antibody [Clone ID: LBI1F7]

Product Specifications

Background

The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca (2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]) . [supplied by OMIM]

Overview

Carrier-free (BSA/glycerol-free) NMNAT1 mouse monoclonal antibody, clone LBI1F7

Synonyms

LCA9; NMNAT; PNAT1; SHILCA

Gene Name

Homo sapiens nicotinamide nucleotide adenylyltransferase 1 (NMNAT1), transcript variant 1, mRNA.

Gene ID

64802

UniProt

Q9HAN9

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Nicotinate and nicotinamide metabolism

Field of Research

Metabolic pathways, Nicotinate and nicotinamide metabolism

Dilution

WB 1:2000, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.