HDAC6 Mouse Monoclonal Antibody [Clone ID: LBI3E7]

Product Specifications

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) HDAC6 mouse monoclonal antibody, clone LBI3E7

Synonyms

CPBHM; HD6; JM21; PPP1R90

Gene Name

Homo sapiens histone deacetylase 6 (HDAC6), transcript variant 5, mRNA.

Gene ID

10013

UniProt

Q9UBN7

Conjugation

Unconjugated

Dilution

WB 1:500~1000, IHC 1:150, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.