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Alpha 1 Fetoprotein (AFP) Mouse Monoclonal Antibody [Clone ID: LBI2E2]

Product Specifications

Background

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) AFP mouse monoclonal antibody, clone LBI2E2

Synonyms

AFPD; FETA; HPAFP

Gene Name

Homo sapiens alpha fetoprotein (AFP), transcript variant 1, mRNA.

Gene ID

174

UniProt

P02771

Conjugation

Unconjugated

Dilution

WB: 1:200 - 1:1000, IF 1:100, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Secreted Protein

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

AFP

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=174

Uniprot URL

https://www.uniprot.org/uniprot/P02771

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