QPRT Mouse Monoclonal Antibody [Clone ID: LBI4B4]

Product Specifications

Background

This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

Overview

Carrier-free (BSA/glycerol-free) QPRT mouse monoclonal antibody, clone LBI4B4

Synonyms

HEL-S-90n; QPRTase

Gene Name

Homo sapiens quinolinate phosphoribosyltransferase (QPRT), transcript variant 1, mRNA.

Gene ID

23475

UniProt

Q15274

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Nicotinate and nicotinamide metabolism

Field of Research

Metabolic pathways, Nicotinate and nicotinamide metabolism

Dilution

WB 1:500~2000, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.