QPRT Mouse Monoclonal Antibody [Clone ID: LBI4E6]
Product Specifications
Background
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Synonyms
HEL-S-90n; QPRTase
Gene Name
Homo sapiens quinolinate phosphoribosyltransferase (QPRT), transcript variant 1, mRNA.
Gene ID
23475
UniProt
Q15274
Conjugation
Unconjugated
Related Pathways
Metabolic pathways, Nicotinate and nicotinamide metabolism
Field of Research
Metabolic pathways, Nicotinate and nicotinamide metabolism
Dilution
WB 1:500~2000, IHC 1:150, FLOW 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
QPRT
Overview
Carrier-free (BSA/glycerol-free) QPRT mouse monoclonal antibody, clone LBI4E6
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=23475
Uniprot URL
https://www.uniprot.org/uniprot/Q15274
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