PAICS Mouse Monoclonal Antibody [Clone ID: LBI8A1]
Product Specifications
Background
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms
ADE2; ADE2H1; AIRC; PAIS
Gene Name
Homo sapiens phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase (PAICS), transcript variant 2, mRNA.
Gene ID
10606
UniProt
P22234
Conjugation
Unconjugated
Related Pathways
Metabolic pathways, Purine metabolism
Field of Research
Metabolic pathways, Purine metabolism
Dilution
WB 1:500~2000, IF 1:100, FLOW 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PAICS
Overview
Carrier-free (BSA/glycerol-free) PAICS mouse monoclonal antibody, clone LBI8A1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10606
Uniprot URL
https://www.uniprot.org/uniprot/P22234
Curated Selection
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