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Glucose 6 phosphate isomerase (GPI) Mouse Monoclonal Antibody [Clone ID: LBI5G9]

Product Specifications

Background

This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

Synonyms

AMF; GNPI; NLK; PGI; PHI; SA-36; SA36

Gene Name

Homo sapiens glucose-6-phosphate isomerase (GPI), transcript variant 2, mRNA.

Gene ID

2821

UniProt

P06744

Conjugation

Unconjugated

Related Pathways

Amino sugar and nucleotide sugar metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway, Starch and sucrose metabolism

Field of Research

Amino sugar and nucleotide sugar metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway, Starch and sucrose metabolism

Dilution

WB 1:2000, IHC 1:50, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

GPI

Overview

Carrier-free (BSA/glycerol-free) GPI mouse monoclonal antibody, clone LBI5G9

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=2821

Uniprot URL

https://www.uniprot.org/uniprot/P06744

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