MCL1 Mouse Monoclonal Antibody [Clone ID: LBI10F6]
Product Specifications
Background
The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.
Synonyms
Bcl2-L-3; BCL2L3; EAT; Mcl-1; MCL1-ES; mcl1/EAT; MCL1L; MCL1S; TM
Gene Name
Homo sapiens MCL1 apoptosis regulator, BCL2 family member (MCL1), transcript variant 1, mRNA.
Gene ID
4170
UniProt
Q07820
Conjugation
Unconjugated
Dilution
WB 1:200 - 1:1000, IHC 1:50, IF 1:100, Flow 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
MCL1
Overview
Carrier-free (BSA/glycerol-free) MCL1 mouse monoclonal antibody, clone LBI10F6
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4170
Uniprot URL
https://www.uniprot.org/uniprot/Q07820
Curated Selection
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