XRCC1 Mouse Monoclonal Antibody [Clone ID: LBI2G8]
Product Specifications
Background
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
Synonyms
RCC
Gene Name
Homo sapiens X-ray repair cross complementing 1 (XRCC1), mRNA.
Gene ID
7515
UniProt
P18887
Conjugation
Unconjugated
Related Pathways
Base excision repair
Field of Research
Base excision repair
Dilution
WB 1:2000, FLOW 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
XRCC1
Overview
Carrier-free (BSA/glycerol-free) XRCC1 mouse monoclonal antibody, clone LBI2G8
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7515
Uniprot URL
https://www.uniprot.org/uniprot/P18887
Curated Selection
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