XRCC1 Mouse Monoclonal Antibody [Clone ID: LBI2G8]

Product Specifications

Background

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) XRCC1 mouse monoclonal antibody, clone LBI2G8

Synonyms

RCC

Gene Name

Homo sapiens X-ray repair cross complementing 1 (XRCC1), mRNA.

Gene ID

7515

UniProt

P18887

Conjugation

Unconjugated

Related Pathways

Base excision repair

Field of Research

Base excision repair

Dilution

WB 1:2000, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.