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LOX Mouse Monoclonal Antibody [Clone ID: LBI3C3]

Product Specifications

Background

The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I) . Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) LOX mouse monoclonal antibody, clone LBI3C3

Synonyms

MGC105112

Gene Name

Homo sapiens lysyl oxidase (LOX), transcript variant 1, mRNA.

Gene ID

4015

UniProt

P28300

Conjugation

Unconjugated

Dilution

WB 1:2000, IF 1:100, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Secreted Protein

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

LOX

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=4015

Uniprot URL

https://www.uniprot.org/uniprot/P28300

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