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PKMYT1 Mouse Monoclonal Antibody [Clone ID: LBI2B4]

Product Specifications

Background

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) PKMYT1 mouse monoclonal antibody, clone LBI2B4

Synonyms

MYT1; PPP1R126

Gene Name

Homo sapiens protein kinase, membrane associated tyrosine/threonine 1 (PKMYT1), transcript variant 1, mRNA.

Gene ID

9088

UniProt

Q99640

Conjugation

Unconjugated

Related Pathways

Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation

Field of Research

Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation

Dilution

IHC 1:100~200, WB: 1:200

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Protein Kinase

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

PKMYT1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=9088

Uniprot URL

https://www.uniprot.org/uniprot/Q99640

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