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ATP5F1B Mouse Monoclonal Antibody [Clone ID: LBI1F7]

Product Specifications

Background

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c) . This gene encodes the beta subunit of the catalytic core.

Overview

Carrier-free (BSA/glycerol-free) ATP5B mouse monoclonal antibody, clone LBI1F7

Synonyms

ATPMB; ATPSB; HEL-S-271

Gene Name

Homo sapiens ATP synthase F1 subunit beta (ATP5F1B), mRNA; nuclear gene for mitochondrial product.

Gene ID

506

UniProt

P06576

Conjugation

Unconjugated

Related Pathways

Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

Field of Research

Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

Dilution

WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

ATP5F1B

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=506

Uniprot URL

https://www.uniprot.org/uniprot/P06576

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