ID3 Mouse Monoclonal Antibody [Clone ID: LBI7B6]
Product Specifications
Background
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
Overview
Carrier-free (BSA/glycerol-free) ID3 mouse monoclonal antibody, clone LBI7B6
Synonyms
BHLHb25; HEIR-1
Gene Name
Homo sapiens inhibitor of DNA binding 3, HLH protein (ID3), mRNA.
Gene ID
3399
UniProt
Q02535
Conjugation
Unconjugated
Related Pathways
TGF-beta signaling pathway
Field of Research
TGF-beta signaling pathway
Dilution
WB 1:2000, IHC 1:50, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
ID3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3399
Uniprot URL
https://www.uniprot.org/uniprot/Q02535
Curated Selection
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