FKBP51 (FKBP5) Mouse Monoclonal Antibody [Clone ID: LBI3E9]

Product Specifications

Background

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition.It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Overview

Carrier-free (BSA/glycerol-free) FKBP5 mouse monoclonal antibody, clone LBI3E9

Synonyms

AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10

Gene Name

Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 1, mRNA.

Gene ID

2289

UniProt

Q13451

Conjugation

Unconjugated

Dilution

WB 1:2000, IHC 1:50, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.