BubR1 (BUB1B) Mouse Monoclonal Antibody [Clone ID: LBI3D9]

Product Specifications

Background

This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

Overview

Carrier-free (BSA/glycerol-free) BUB1B mouse monoclonal antibody, clone LBI3D9

Synonyms

Bub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1

Gene Name

Homo sapiens BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B), mRNA.

Gene ID

701

UniProt

O60566

Conjugation

Unconjugated

Related Pathways

Cell cycle

Field of Research

Cell cycle

Dilution

WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Protein Kinase, Stem cell - Pluripotency

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.