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Cytochrome P450 Reductase (POR) Mouse Monoclonal Antibody [Clone ID: LBI3H10]

Product Specifications

Background

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

Synonyms

CPR; CYPOR; P450R

Gene Name

Homo sapiens cytochrome p450 oxidoreductase (POR), transcript variant 2, mRNA.

Gene ID

5447

UniProt

P16435

Conjugation

Unconjugated

Dilution

WB 1:1000, IHC 1:50, IF 1:100, Flow 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, P450, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

POR

Overview

Carrier-free (BSA/glycerol-free) POR mouse monoclonal antibody, clone LBI3H10

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=5447

Uniprot URL

https://www.uniprot.org/uniprot/P16435

Curated Selection

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