Cytochrome P450 Reductase (POR) Mouse Monoclonal Antibody [Clone ID: LBI3H10]
Selected Variant
AMM09237VCF
Size: 100 µg
Product Specifications
Background
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Overview
Carrier-free (BSA/glycerol-free) POR mouse monoclonal antibody, clone LBI3H10
Synonyms
CPR; CYPOR; P450R
Gene Name
Homo sapiens cytochrome p450 oxidoreductase (POR), transcript variant 2, mRNA.
Gene ID
5447
UniProt
P16435
Conjugation
Unconjugated
Dilution
WB 1:1000, IHC 1:50, IF 1:100, Flow 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, P450, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
POR
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5447
Uniprot URL
https://www.uniprot.org/uniprot/P16435
Price
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