KDM4C Mouse Monoclonal Antibody [Clone ID: LBI5B9]
Product Specifications
Background
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
Synonyms
GASC1; JHDM3C; JMJD2C; TDRD14C
Gene Name
Homo sapiens lysine demethylase 4C (KDM4C), transcript variant 1, mRNA.
Gene ID
23081
UniProt
Q9H3R0
Conjugation
Unconjugated
Dilution
WB 1:2000, IHC 1:50, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
KDM4C
Overview
Carrier-free (BSA/glycerol-free) KDM4C mouse monoclonal antibody, clone LBI5B9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=23081
Uniprot URL
https://www.uniprot.org/uniprot/Q9H3R0
Curated Selection
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