KDM4C Mouse Monoclonal Antibody [Clone ID: LBI5B9]

Product Specifications

Background

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Overview

Carrier-free (BSA/glycerol-free) KDM4C mouse monoclonal antibody, clone LBI5B9

Synonyms

GASC1; JHDM3C; JMJD2C; TDRD14C

Gene Name

Homo sapiens lysine demethylase 4C (KDM4C), transcript variant 1, mRNA.

Gene ID

23081

UniProt

Q9H3R0

Conjugation

Unconjugated

Dilution

WB 1:2000, IHC 1:50, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.