DHFR Mouse Monoclonal Antibody [Clone ID: LBI6G7]
Product Specifications
Background
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.
Synonyms
DHFRP1; DYR
Gene Name
Homo sapiens dihydrofolate reductase (DHFR), transcript variant 1, mRNA.
Gene ID
1719
UniProt
P00374
Conjugation
Unconjugated
Related Pathways
Folate biosynthesis, Metabolic pathways, One carbon pool by folate
Field of Research
Folate biosynthesis, Metabolic pathways, One carbon pool by folate
Dilution
WB 1:2000 IHC 1:50 IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Stem cell - Pluripotency
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
DHFR
Overview
Carrier-free (BSA/glycerol-free) DHFR mouse monoclonal antibody, clone LBI6G7
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1719
Uniprot URL
https://www.uniprot.org/uniprot/P00374
Curated Selection
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