DHFR Mouse Monoclonal Antibody [Clone ID: LBI6G7]

Product Specifications

Background

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.

Overview

Carrier-free (BSA/glycerol-free) DHFR mouse monoclonal antibody, clone LBI6G7

Synonyms

DHFRP1; DYR

Gene Name

Homo sapiens dihydrofolate reductase (DHFR), transcript variant 1, mRNA.

Gene ID

1719

UniProt

P00374

Conjugation

Unconjugated

Related Pathways

Folate biosynthesis, Metabolic pathways, One carbon pool by folate

Field of Research

Folate biosynthesis, Metabolic pathways, One carbon pool by folate

Dilution

WB 1:2000 IHC 1:50 IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Stem cell - Pluripotency

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.