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STAT1 Mouse Monoclonal Antibody [Clone ID: LBI4H9]

Product Specifications

Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]

Synonyms

CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91

Gene Name

Homo sapiens signal transducer and activator of transcription 1 (STAT1), transcript variant beta, mRNA.

Gene ID

6772

UniProt

P42224

Conjugation

Unconjugated

Related Pathways

Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer, Toll-like receptor signaling pathway

Field of Research

Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer, Toll-like receptor signaling pathway

Dilution

WB 1:1000~2000, IHC 1:50, IF 1:50~100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

STAT1

Overview

Carrier-free (BSA/glycerol-free) STAT1 mouse monoclonal antibody, clone LBI4H9

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=6772

Uniprot URL

https://www.uniprot.org/uniprot/P42224

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