IRF3 Mouse Monoclonal Antibody [Clone ID: LBI5D2]
Product Specifications
Background
IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.
Synonyms
IIAE7
Gene Name
Homo sapiens interferon regulatory factor 3 (IRF3), transcript variant 1, mRNA.
Gene ID
3661
UniProt
Q14653
Conjugation
Unconjugated
Related Pathways
Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Field of Research
Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Dilution
WB 1:2000 IHC 1:50
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
IRF3
Overview
Carrier-free (BSA/glycerol-free) IRF3 mouse monoclonal antibody, clone LBI5D2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3661
Uniprot URL
https://www.uniprot.org/uniprot/Q14653
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