IRF3 Mouse Monoclonal Antibody [Clone ID: LBI5D2]

Product Specifications

Background

IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.

Overview

Carrier-free (BSA/glycerol-free) IRF3 mouse monoclonal antibody, clone LBI5D2

Synonyms

IIAE7

Gene Name

Homo sapiens interferon regulatory factor 3 (IRF3), transcript variant 1, mRNA.

Gene ID

3661

UniProt

Q14653

Conjugation

Unconjugated

Related Pathways

Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway

Field of Research

Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway

Dilution

WB 1:2000 IHC 1:50

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.