Melanoma gp100 (PMEL) Mouse Monoclonal Antibody [Clone ID: LBI7E3]
Product Specifications
Background
Could be a melanogenic enzyme. Could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Overview
Carrier-free (BSA/glycerol-free) SILV mouse monoclonal antibody, clone LBI7E3
Synonyms
D12S53E; gp100; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV
Gene Name
Homo sapiens premelanosome protein (PMEL), transcript variant 3, mRNA.
Gene ID
6490
UniProt
P40967
Conjugation
Unconjugated
Dilution
FLOW 1:100, IHC: 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Secreted Protein, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PMEL
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6490
Uniprot URL
https://www.uniprot.org/uniprot/P40967
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