Melanoma gp100 (PMEL) Mouse Monoclonal Antibody [Clone ID: LBI10E5]

Product Specifications

Background

Could be a melanogenic enzyme. Could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity

Overview

Carrier-free (BSA/glycerol-free) SILV mouse monoclonal antibody, clone LBI10E5

Synonyms

D12S53E; gp100; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV

Gene Name

Homo sapiens premelanosome protein (PMEL), transcript variant 3, mRNA.

Gene ID

6490

UniProt

P40967

Conjugation

Unconjugated

Dilution

WB 1:1000 IHC 1:50 IF 1:100 Flow 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Secreted Protein, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.