TrkB (NTRK2) Mouse Monoclonal Antibody [Clone ID: LBI2E1]
Product Specifications
Background
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene
Synonyms
GP145-TrkB; OBHD; trk-B; TRKB
Gene Name
Homo sapiens neurotrophic receptor tyrosine kinase 2 (NTRK2), transcript variant b, mRNA.
Gene ID
4915
UniProt
Q16620
Conjugation
Unconjugated
Related Pathways
MAPK signaling pathway, Neurotrophin signaling pathway
Field of Research
MAPK signaling pathway, Neurotrophin signaling pathway
Dilution
WB 1:1000, IHC 1:150, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Protein Kinase, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NTRK2
Overview
Carrier-free (BSA/glycerol-free) NTRK2 mouse monoclonal antibody, clone LBI2E1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4915
Uniprot URL
https://www.uniprot.org/uniprot/Q16620
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