VEGFA Mouse Monoclonal Antibody [Clone ID: LBI4E3]
Product Specifications
Background
VEGF is a member of the PDGF/VEGF growth factor family that is often found as a disulfide linked homodimer. It is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGF gene have been associated with proliferative and nonproliferative diabetic retinopathy.
Synonyms
MVCD1; VEGF; VPF
Gene Name
Homo sapiens vascular endothelial growth factor A (VEGFA), transcript variant 1, mRNA.
Gene ID
7422
UniProt
P15692
Conjugation
Unconjugated
Related Pathways
Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma, VEGF signaling pathway
Field of Research
Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma, VEGF signaling pathway
Dilution
WB: 1:200 - 1:1000, IHC 1:50, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Secreted Protein
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
VEGFA
Overview
Carrier-free (BSA/glycerol-free) VEGF mouse monoclonal antibody, clone LBI4E3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7422
Uniprot URL
https://www.uniprot.org/uniprot/P15692
Curated Selection
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