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IL6 Mouse Monoclonal Antibody [Clone ID: LBI3H6]

Product Specifications

Background

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.

Overview

Carrier-free (BSA/glycerol-free) IL-6 mouse monoclonal antibody, clone LBI3H6

Synonyms

BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6

Gene Name

Homo sapiens interleukin 6 (IL6), transcript variant 1, mRNA.

Gene ID

3569

UniProt

P05231

Conjugation

Unconjugated

Related Pathways

Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Jak-STAT signaling pathway, NOD-like receptor signaling pathway, Pathways in cancer, Prion diseases, Toll-like receptor signaling pathway

Field of Research

Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Jak-STAT signaling pathway, NOD-like receptor signaling pathway, Pathways in cancer, Prion diseases, Toll-like receptor signaling pathway

Dilution

WB 1:1000; IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Secreted Protein

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

IL6

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=3569

Uniprot URL

https://www.uniprot.org/uniprot/P05231

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