Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody [Clone ID: LBI1B12]
Product Specifications
Background
Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Synonyms
CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
Gene Name
Homo sapiens keratin 8 (KRT8), transcript variant 2, mRNA.
Gene ID
3856
UniProt
P05787
Conjugation
Unconjugated
Dilution
WB 1:2500~5000, IHC 1:50 - 1:150, IF 1:50 - 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
KRT8
Overview
Carrier-free (BSA/glycerol-free) CK8 mouse monoclonal antibody, clone LBI1B12
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3856
Uniprot URL
https://www.uniprot.org/uniprot/P05787
Curated Selection
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