Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody [Clone ID: LBI1B12]

Product Specifications

Background

Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Overview

Carrier-free (BSA/glycerol-free) CK8 mouse monoclonal antibody, clone LBI1B12

Synonyms

CARD2; CK-8; CK8; CYK8; K2C8; K8; KO

Gene Name

Homo sapiens keratin 8 (KRT8), transcript variant 2, mRNA.

Gene ID

3856

UniProt

P05787

Conjugation

Unconjugated

Dilution

WB 1:2500~5000, IHC 1:50 - 1:150, IF 1:50 - 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.