MSH2 Mouse Monoclonal Antibody [Clone ID: UMLBI259]
Product Specifications
Background
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Overview
Carrier-free (BSA/glycerol-free) MSH2 mouse monoclonal antibody, clone UMLBI259
Synonyms
COCA1; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; MMRCS2
Gene Name
Homo sapiens mutS homolog 2 (MSH2), transcript variant 1, mRNA.
Gene ID
4436
UniProt
P43246
Conjugation
Unconjugated
Related Pathways
Colorectal cancer, Mismatch repair, Pathways in cancer
Field of Research
Colorectal cancer, Mismatch repair, Pathways in cancer
Dilution
IHC 1:2400
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Stem cell - Pluripotency
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
MSH2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4436
Uniprot URL
https://www.uniprot.org/uniprot/P43246
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