AMACR Mouse Monoclonal Antibody [Clone ID: UMLBI214]

Product Specifications

Background

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R) - and (S) -stereoisomers. The conversion to the (S) -stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]

Overview

Carrier-free (BSA/glycerol-free) AMACR mouse monoclonal antibody, clone UMLBI214

Synonyms

AMACRD; CBAS4; RACE; RM

Gene Name

Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1, mRNA.

Gene ID

23600

UniProt

Q9UHK6

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Primary bile acid biosynthesis

Field of Research

Metabolic pathways, Primary bile acid biosynthesis

Dilution

IHC 1:100~2400

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.