HMBS Mouse Monoclonal Antibody [Clone ID: UMLBI144]

Product Specifications

Background

This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) HMBS mouse monoclonal antibody, clone UMLBI144

Synonyms

PBG-D; PBGD; PORC; UPS

Gene Name

Homo sapiens hydroxymethylbilane synthase (HMBS), transcript variant 1, mRNA.

Gene ID

3145

UniProt

P08397

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Porphyrin and chlorophyll metabolism

Field of Research

Metabolic pathways, Porphyrin and chlorophyll metabolism

Dilution

WB 1:2000, IHC 1:200

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.