B7-1 (CD80) Mouse Monoclonal Antibody [Clone ID: UMLBI65]

Product Specifications

Background

The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]

Overview

Carrier-free (BSA/glycerol-free) CD80 mouse monoclonal antibody, clone UMLBI65

Synonyms

B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7

Gene Name

Homo sapiens CD80 molecule (CD80), mRNA.

Gene ID

941

UniProt

P33681

Conjugation

Unconjugated

Related Pathways

Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis

Field of Research

Dilution

IHC 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.