B7-1 (CD80) Mouse Monoclonal Antibody [Clone ID: UMLBI65]
Product Specifications
Background
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]
Overview
Carrier-free (BSA/glycerol-free) CD80 mouse monoclonal antibody, clone UMLBI65
Synonyms
B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7
Gene Name
Homo sapiens CD80 molecule (CD80), mRNA.
Gene ID
941
UniProt
P33681
Conjugation
Unconjugated
Related Pathways
Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis
Field of Research
Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis
Dilution
IHC 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transcription Factors, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CD80
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=941
Uniprot URL
https://www.uniprot.org/uniprot/P33681
Curated Selection
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