ALDH1L1 Mouse Monoclonal Antibody [Clone ID: UMLBI43]

Product Specifications

Background

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

Overview

Carrier-free (BSA/glycerol-free) ALDH1L1 mouse monoclonal antibody, clone UMLBI43

Synonyms

10-fTHF; 10-FTHFDH; FDH; FTHFD

Gene Name

Homo sapiens aldehyde dehydrogenase 1 family member L1 (ALDH1L1), transcript variant 2, mRNA.

Gene ID

10840

UniProt

O75891

Conjugation

Unconjugated

Related Pathways

One carbon pool by folate

Field of Research

One carbon pool by folate

Dilution

WB 1:500, IHC 1:400, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.