ALDH1L1 Mouse Monoclonal Antibody [Clone ID: UMLBI43]
Product Specifications
Background
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Synonyms
10-fTHF; 10-FTHFDH; FDH; FTHFD
Gene Name
Homo sapiens aldehyde dehydrogenase 1 family member L1 (ALDH1L1), transcript variant 2, mRNA.
Gene ID
10840
UniProt
O75891
Conjugation
Unconjugated
Related Pathways
One carbon pool by folate
Field of Research
One carbon pool by folate
Dilution
WB 1:500, IHC 1:400, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
ALDH1L1
Overview
Carrier-free (BSA/glycerol-free) ALDH1L1 mouse monoclonal antibody, clone UMLBI43
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10840
Uniprot URL
https://www.uniprot.org/uniprot/O75891
Curated Selection
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