CD133 (PROM1) Mouse Monoclonal Antibody [Clone ID: LBI5G10]

Product Specifications

Background

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

Overview

Carrier-free (BSA/glycerol-free) PROM1 mouse monoclonal antibody, clone LBI5G10

Synonyms

AC133; CD133; CORD12; MCDR2; MSTP061; PROML1; RP41; STGD4

Gene Name

Homo sapiens prominin 1 (PROM1), transcript variant 1, mRNA.

Gene ID

8842

UniProt

O43490

Conjugation

Unconjugated

Dilution

WB 1:1000, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.