MICB Mouse Monoclonal Antibody [Clone ID: LBI3E6]
Product Specifications
Background
This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Overview
Carrier-free (BSA/glycerol-free) MICB mouse monoclonal antibody, clone LBI3E6
Synonyms
PERB11.2
Gene Name
Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 1, mRNA.
Gene ID
4277
UniProt
Q29980
Conjugation
Unconjugated
Related Pathways
Natural killer cell mediated cytotoxicity
Field of Research
Natural killer cell mediated cytotoxicity
Dilution
WB 1:1000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
MICB
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4277
Uniprot URL
https://www.uniprot.org/uniprot/Q29980
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