Arginase 1 (ARG1) Mouse Monoclonal Antibody [Clone ID: LBI2E7]

Product Specifications

Background

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Overview

Carrier-free (BSA/glycerol-free) ARG1 mouse monoclonal antibody, clone LBI2E7

Synonyms

Arginase, liver; arginase 1; liver-type arginase; OTTHUMP00000017209; type I arginase

Gene Name

Homo sapiens arginase 1 (ARG1), transcript variant 2, mRNA.

Gene ID

383

UniProt

P05089

Conjugation

Unconjugated

Related Pathways

Arginine and proline metabolism, Metabolic pathways

Field of Research

Arginine and proline metabolism, Metabolic pathways

Dilution

WB 1:500 IHC 1:8000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.