Arginase 1 (ARG1) Mouse Monoclonal Antibody [Clone ID: LBI4H7]
Product Specifications
Background
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Synonyms
Arginase, liver; arginase 1; liver-type arginase; OTTHUMP00000017209; type I arginase
Gene Name
Homo sapiens arginase 1 (ARG1), transcript variant 2, mRNA.
Gene ID
383
UniProt
P05089
Conjugation
Unconjugated
Related Pathways
Arginine and proline metabolism, Metabolic pathways
Field of Research
Arginine and proline metabolism, Metabolic pathways
Dilution
WB 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
ARG1
Overview
Carrier-free (BSA/glycerol-free) ARG1 mouse monoclonal antibody, clone LBI4H7
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=383
Uniprot URL
https://www.uniprot.org/uniprot/P05089
Curated Selection
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