PDZK1 Mouse Monoclonal Antibody [Clone ID: LBI2B4]

Product Specifications

Background

This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Overview

Carrier-free (BSA/glycerol-free) PDZK1 mouse monoclonal antibody, clone LBI2B4

Synonyms

CAP70; CLAMP; NHERF-3; NHERF3; PDZD1

Gene Name

Homo sapiens PDZ domain containing 1 (PDZK1), transcript variant 1, mRNA.

Gene ID

5174

UniProt

Q5T2W1

Conjugation

Unconjugated

Dilution

WB 1:250~2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.