JAK3 Mouse Monoclonal Antibody [Clone ID: LBI2B4]
Product Specifications
Background
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) . [provided by RefSeq, Jul 2008]
Overview
Carrier-free (BSA/glycerol-free) JAK3 mouse monoclonal antibody, clone LBI2B4
Synonyms
JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK
Gene Name
Homo sapiens Janus kinase 3 (JAK3), mRNA.
Gene ID
3718
UniProt
P52333
Conjugation
Unconjugated
Related Pathways
Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency
Field of Research
Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency
Dilution
WB 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Protein Kinase
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
JAK3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3718
Uniprot URL
https://www.uniprot.org/uniprot/P52333
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