Syntaxin 1a (STX1A) Mouse Monoclonal Antibody [Clone ID: LBI1D8]

Product Specifications

Background

This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein) -Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc) . Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Overview

Carrier-free (BSA/glycerol-free) STX1A mouse monoclonal antibody, clone LBI1D8

Synonyms

HPC-1; P35-1; STX1; SYN1A

Gene Name

Homo sapiens syntaxin 1A (STX1A), transcript variant 1, mRNA.

Gene ID

6804

UniProt

Q16623

Conjugation

Unconjugated

Related Pathways

SNARE interactions in vesicular transport

Field of Research

SNARE interactions in vesicular transport

Dilution

WB 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Secreted Protein, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.