Xanthine Oxidase (XDH) Mouse Monoclonal Antibody [Clone ID: LBI1C10]
Product Specifications
Background
Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014]
Synonyms
XAN1; XO; XOR
Gene Name
Homo sapiens xanthine dehydrogenase (XDH), mRNA.
Gene ID
7498
UniProt
P47989
Conjugation
Unconjugated
Related Pathways
Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism
Field of Research
Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism
Dilution
WB 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
XDH
Overview
Carrier-free (BSA/glycerol-free) XDH mouse monoclonal antibody, clone LBI1C10
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7498
Uniprot URL
https://www.uniprot.org/uniprot/P47989
Curated Selection
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