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Xanthine Oxidase (XDH) Mouse Monoclonal Antibody [Clone ID: LBI1C10]

Product Specifications

Background

Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014]

Overview

Carrier-free (BSA/glycerol-free) XDH mouse monoclonal antibody, clone LBI1C10

Synonyms

XAN1; XO; XOR

Gene Name

Homo sapiens xanthine dehydrogenase (XDH), mRNA.

Gene ID

7498

UniProt

P47989

Conjugation

Unconjugated

Related Pathways

Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism

Field of Research

Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism

Dilution

WB 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

XDH

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=7498

Uniprot URL

https://www.uniprot.org/uniprot/P47989

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