PSMA1 Mouse Monoclonal Antibody [Clone ID: LBI9H1]

Product Specifications

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2009]

Overview

Carrier-free (BSA/glycerol-free) PSMA1 mouse monoclonal antibody, clone LBI9H1

Synonyms

HC2; HEL-S-275; NU; PROS30

Gene Name

Homo sapiens proteasome 20S subunit alpha 1 (PSMA1), transcript variant 2, mRNA.

Gene ID

5682

UniProt

P25786

Conjugation

Unconjugated

Related Pathways

Proteasome

Field of Research

Proteasome

Dilution

WB 1:250, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Protease

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.