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GTF3C4 Mouse Monoclonal Antibody [Clone ID: LBI4A3]

Product Specifications

Background

Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box. [UniProtKB/Swiss-Prot Function]

Synonyms

KAT12; TF3C-delta; TFIII90; TFIIIC90; TFIIIC290; TFIIICDELTA

Gene Name

Homo sapiens general transcription factor IIIC subunit 4 (GTF3C4), transcript variant 1, mRNA.

Gene ID

9329

UniProt

Q9UKN8

Conjugation

Unconjugated

Dilution

WB 1:500, IHC 1:750

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

GTF3C4

Overview

Carrier-free (BSA/glycerol-free) GTF3C4 mouse monoclonal antibody, clone LBI4A3

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=9329

Uniprot URL

https://www.uniprot.org/uniprot/Q9UKN8

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