IL28 Receptor alpha (IFNLR1) Mouse Monoclonal Antibody [Clone ID: LBI7B2]

Product Specifications

Background

The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB) . The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29) . The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) IFNLR1 mouse monoclonal antibody, clone LBI7B2

Synonyms

CRF2/12; IFNLR; IL-28R1; IL28RA; LICR2

Gene Name

Homo sapiens interferon lambda receptor 1 (IFNLR1), transcript variant 1, mRNA.

Gene ID

163702

UniProt

Q8IU57

Conjugation

Unconjugated

Related Pathways

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Field of Research

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Dilution

WB 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.