TIM 3 (HAVCR2) Mouse Monoclonal Antibody [Clone ID: LBI1C4]
Product Specifications
Background
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]
Synonyms
CD366; HAVcr-2; KIM-3; SPTCL; Tim-3; TIM3; TIMD-3; TIMD3
Gene Name
Homo sapiens hepatitis A virus cellular receptor 2 (HAVCR2), mRNA.
Gene ID
84868
UniProt
Q8TDQ0
Conjugation
Unconjugated
Dilution
WB 1:500, FLOW 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
HAVCR2
Overview
Carrier-free (BSA/glycerol-free) HAVCR2 mouse monoclonal antibody, clone LBI1C4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=84868
Uniprot URL
https://www.uniprot.org/uniprot/Q8TDQ0
Curated Selection
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