HB EGF (HBEGF) Mouse Monoclonal Antibody [Clone ID: LBI6F4]
Product Specifications
Background
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. [UniProtKB/Swiss-Prot Function]
Overview
Carrier-free (BSA/glycerol-free) HBEGF mouse monoclonal antibody, clone LBI6F4
Synonyms
DTR; DTS; DTSF; HEGFL
Gene Name
Homo sapiens heparin binding EGF like growth factor (HBEGF), mRNA.
Gene ID
1839
UniProt
Q99075
Conjugation
Unconjugated
Related Pathways
Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway
Field of Research
Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Secreted Protein, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
HBEGF
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1839
Uniprot URL
https://www.uniprot.org/uniprot/Q99075
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL711979V 500 µL Each
Atp6v0e1 Rat shRNA Lentiviral Particle (Locus ID 94170)
Sign In for Pricing
View Details 