Gamma Catenin (JUP) Mouse Monoclonal Antibody [Clone ID: LBI1B4]
Product Specifications
Background
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]
Synonyms
CTNNG; DP3; DPIII; PDGB; PG; PKGB
Gene Name
Homo sapiens junction plakoglobin (JUP), transcript variant 1, mRNA.
Gene ID
3728
UniProt
P14923
Conjugation
Unconjugated
Related Pathways
Acute myeloid leukemia, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Pathways in cancer
Field of Research
Acute myeloid leukemia, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Pathways in cancer
Dilution
IHC 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
JUP
Overview
Carrier-free (BSA/glycerol-free) JUP mouse monoclonal antibody, clone LBI1B4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3728
Uniprot URL
https://www.uniprot.org/uniprot/P14923
Curated Selection
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