TNFRSF4 Mouse Monoclonal Antibody [Clone ID: LBI9G3]

Product Specifications

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) TNFRSF4 mouse monoclonal antibody, clone LBI9G3

Synonyms

ACT35; CD134; IMD16; OX40; TXGP1L

Gene Name

Homo sapiens TNF receptor superfamily member 4 (TNFRSF4), mRNA.

Gene ID

7293

UniProt

P43489

Conjugation

Unconjugated

Related Pathways

Cytokine-cytokine receptor interaction

Field of Research

Cytokine-cytokine receptor interaction

Dilution

WB 1:1000, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.